Argentina joined SNOMED International in 2018, adopting SNOMED CT as the standard vocabulary for its national Health Information infrastructure implementation.

Chile became a Member on November 1 2013, joining a global effort to develop, maintain, and enable the use of SNOMED CT in health systems around the world.

El Salvador became a Member in June 2022, joining a global effort to develop, maintain, and enable the use of SNOMED CT in health systems around the world.

The United States representative to SNOMED International is the National Library of Medicine (NLM) on behalf of the US Department of Health and Human Services (HHS).

During 2017 Uruguay continued advancing in the implementation of the National Electronic Health Record (NEHR) project.